Applied Genetic Technologies, an Alachua, Fla., gene-therapy developer, received a $2 million milestone payment from Genzyme.

The two companies are jointly developing a gene therapy for treating a form of blindness called age-related macular degeneration. The treatment uses an adeno-associated virus designed to deliver a gene to eye cells that, when activated, will disrupt a protein called VEGF that stimulates the growth of leaky blood vessels that contribute directly to blindness.

The milestone payment covered the successful transfer of AGT’s adeno-associated virus production technology to Genzyme. The gene-therapy treatment doesn’t appear to be ready for clinical trials yet.

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    [...] other irons in the gene-therapy fire as well; today, Applied Genetic Technologies announced that it received $2 million from the big biotech as a milestone payment for its development of a gene therapy for a particular form of [...]

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2 Comments

  1. June 26th, 2007
    1:52 pm

    Ricardo said:

    Great work being done and Genzyme was smart to pick it up.

    PS: How I deplore websites that resize my browser window. Yes, agtc… I’m talking to you!

  2. June 26th, 2007
    3:52 pm

    David Hamilton said:

    It is interesting, although of course the up-and-down history of gene therapy suggests that this sort of technology has to be viewed with a lot of caution.

    I totally agree about the AGTC Web site — it’s obnoxious.

    Genzyme appears to be increasingly interested in gene therapy. I missed an item from Friday in which they invested a fairly large sum in Ceregene, the Cell Genesys gene-therapy spinoff. I’ll post a link here when I get the item up in a bit.

    UPDATE: The Ceregene-Genzyme item is up here.

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