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Posts Tagged ‘co:Anacor-Pharmaceuticals’

Featured companies: AirInSpace, Anacor Pharmaceuticals, Apollo Endosurgery, Ascension Health Partners, BG Medicine, CeraPedics, GlaxoSmithKline, Simplex Diabetic Supply, Zars Pharma

UPDATED: Last entry added at 2am PT on 10/8/07.

anacor-pharma-logo.jpgAnacor Pharma pulls in $22M from Glaxo, with hundreds of millions more on the line –Palo Alto, Calif.-based Anacor Pharmaceuticals, a biotech developing new anti-infective and anti-inflammatory drugs using boron chemistry, struck a wide-ranging partnership with GlaxoSmithKline worth up to $605 million. Anacor will receive a $12 million cash payment and a $10 million equity investment in exchange for Glaxo options to as many as eight drug candidates.

Anacor is also eligible for milestone payments on each product candidate, although the release is so badly worded it’s difficult to know exactly how much is really on the line. What the release says is that “Anacor is eligible to receive discovery, development, regulatory and commercial milestones ranging up to $252 million and $331 million for each product candidate.” Does that mean a total of $583 million for each candidate, somewhere between $252 million and $331 million, or something else altogether? You’ve got me. I’ve put in calls to both companies, and will update if someone clarifies this.

(UPDATE: A GSK representative finally called back, admitted that the original wording was unclear, and said that any given product candidate could yield maximum potential milestones of between $252 million and $331 million. Whew.)

Anacor is developing a new class of antibiotics, antifungal drugs and anti-inflammatories based on the novel properties of boron, an element that doesn’t feature largely in traditional pharmaceuticals. Its leading candidates target a fungal infection called onychomycosis and the autoimmune skin condition psoriasis. The company filed for a $58 million IPO in August; see our coverage here.

Simplex Diabetic Supply draws $50M for acquisitions — Brentwood, Tenn.-based Simplex Diabetic Supply (no Web site), a provider of diabetic testing supplies, raised $50 million for expansion. New Enterprise Associates provided the funding. Simplex Chairman Richard Pinson said the funding will allow the company to “accelerate and execute” its acquisition strategy. (UPDATE: See a longer take on this deal and what it says about the business strategies of nervous VCs here.)

ascension-health-ventures-logo.jpgAscension Health Ventures launches $200M healthcare fund — Ascension Health Ventures, a St. Louis-based venture firm owned by the Catholic non-profit healthcare provider Ascension Health, launched a new $200 million fund. Ascension Health and two other Catholic health systems — Catholic Health Initiatives and Catholic Health East — provided the funding. The fund will target later-stage medical device, healthcare technology and healthcare service companies. The release is here.

Bone-graft substitutor CeraPedics pulls in $14M — The Lakewood, Colo., maker of a drug-infused putty that stimulates bone regrowth, raised $14.5 million of a $16.5 million first funding round, PE Hub reports, citing a regulatory filing. Orbimed Advisors led the round. CeraPedics makes a bone-graft substitute that relies on a peptide called P-15 that plays an important role initiating the formation of bone.

Apollo Endosurgery raises $11.5M for minimally invasive surgical devices — The Austin, Tex., developer of surgical devices designed for operations that utilize the body’s “natural orifices” raised $11.5 million in a first funding round. Among those providing the funding were PTV Sciences, H.I.G. Ventures, and individual investors. Apollo’s devices are specifically designed for surgeries that utilize the digestive tract in order to access the peritoneal cavity — a technique now being applied to obesity and early-stage cancers.

AirInSpace draws €6M for biodecontamination devices — Paris-based AirInSpace, a developer of devices that identify and neutralize airborne biological hazards, raised €6 million ($8.5 million) in a second funding round. Investors included Matignon Technologies and Oddo AM. AirInSpace makes devices that reduce airborne microbial pathogens, although I’ve read their release and Web site through a few times and I still don’t have a clue exactly how they’re supposed to do that.

AssayDepot gets $1.8M for drug-research service marketplace — San Diego’s AssayDepot, an Internet marketplace for the drug-research services industry, raised $1.8 million in a first funding round. Private investors provided the funding. The company is developing a marketplace intended to allow industry and academic researchers to contract for research services offered around the world.

zars-pharma-logo.jpgZars Pharma abandons IPO — Salt Lake City’s Zars Pharma, which reformulates pain drugs for delivery via skin patches, formally withdrew its proposed IPO, citing “market conditions.” Its SEC filing is here. The last we heard from the company was in late September, when Zars reportedly postponed an IPO that had been scheduled for that week. (See our previous coverage here, here and here.)

The Zars withdrawal doesn’t seem to herald any particular trend in the IPO market, which is still blowing hot and cold on biotech and pharma companies. For instance, MAP Pharmaceuticals, another specialty pharma that went public last Friday, has seen a nice share-price rise of more than 30% since its offering. Two more tests of the biotech IPO market are expected this week: BioHeart (which I covered here) and Targanta Therapeutics (our coverage here and here).

bgmed-logo.jpgDiagnostics maker BG Medicine sets IPO range, aims for €50M — BG Medicine, a Waltham, Mass., maker of molecular diagnostics for heart disease and measuring drug response, now hopes to raise as much as €50 million ($70.8 million) in an IPO. BG Medicine plans to sell as many as 6.9 million shares at a price of €5.75 to €7.25 apiece. We last wrote about the company here.

map-pharma-logo.jpgMAP Pharmaceuticals, the Mountain View, Calif., specialty pharma, had a mixed reception to its IPO Friday. The company priced its shares at $12, below its anticipated range of $14 to $16, raising up to $69 million — substantially less than the $92 million it might have pulled in. Investors, however, reacted positively and pushed up the shares 11 percent to $13.35.

MAP reformulates existing drugs in order to deliver them via inhalers. Its leading product is a new version of the asthma drug budesonide, which is used to treat pediatric asthma. See our previous coverage of the company here (second item) and here.

Some other recent filings that slipped through the cracks:

anacor-pharma-logo.jpgAnti-infective developer Anacor Pharma looks for $58M IPO — Palo Alto, Calif.-based Anacor Pharmaceuticals, a biotech developing new antibiotics, anti-inflammatories and antifungal drugs, filed to raise up to $57.5 million in an IPO on Aug. 31. The company, which develops new drugs from a process focused on the chemistry of boron, is focused first on topical medications for fungal nail infections known as onychomycosis and the autoimmune skin condition psoriasis. See our previous coverage of the company here.

emphasys-medical.jpgEmphasys Medical targets $86M IPO for lung devices — Redwood City, Calif.-based Emphasys Medical, a device maker focused on treatments for emphysema and similar lung diseases, filed on Sept. 21 to raise up to $86.3 million in an IPO. The company makes insertable one-way valves for the bronchial tubes that move air in and out of the lungs; these valves can “close off” diseased and overinflated parts of the lung in order to enable the remaining healthy areas to function normally.

As part of its SEC filing, Emphasys also disclosed the results of a pivotal trial of its device, known as the Emphasys Bronchial Valve, or EBV. In that randomized trial of 321 patients, those who received the EBV saw exhaled air volume — a sign of lung health — 6.4 percent greater than that of untreated patients. Patients treated with the device were also able to walk 5.6 percent farther in six minutes than the control group.

monosol-rx-logo.jpgDrug formulator MonoSol Rx sets IPO price range, hopes for $83M — MonoSol Rx, a Warren, N.J., maker of drug formulations designed to mask the taste of particular medications, says it hopes to raise up to $82.8 million in an IPO. The company plans to sell up to 4.6 million shares at a price of $16 to $18 apiece, it said in a filing on Oct. 3. MonoSol Rx makes quick-dissolving “thin films” that can be used to repackage existing drugs into easy-to-swallow forms.

merrion-logo.jpgIrish reformulator Merrion Pharma hopes for $55M IPO — Dublin’s Merrion Pharmaceuticals, a developer of drug formulations that improve absorption within the gastrointestinal tract, aims to raise up to $55.2 million in an IPO. The company plans to offer four million shares as American Depositary Shares at a price of $10 to $12 apiece. Merrion’s technology is designed to reformulate drugs that can only be injected into pill or gel capsule forms.

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