diaDexus lands $9.2M for cardiovascular diagnostics
South San Francisco, Calif. biotech firm diaDexus just raised $9.2 million in sixth-round funding from Scale Venture Partners, GlaxoSithKline and Baker Brothers Advisors, according to peHUB. The company’s first and only product, the PLAC Test, is used to detect early indicators of risk for heart attack and stroke. If such conditions can be determined at an early stage, aggressive treatment can prevent possibly-fatal events from ever occurring, diaDexus claims.
Founded in 2000, the company had… Continue Reading
Cancer drug developer ChemoCentryx cancels IPO
Mountain View, Calif.-based biotech firm ChemoCentryx announced that it withdrew its filing to go public, citing (as per usual) unfavorable market conditions. The company, which develops drugs to treat cancer and autoimmune ailments like Crohn’s disease, raked in $50 million from its partner GlaxoSmithKline just last month, but the downturn-prompted freeze on IPOs has yet to thaw.
While only four health care companies have been able to go public this year, the company says that the… Continue Reading
ChemoCentryx raises $50M, eyes bleak IPO landscape for biotech
ChemoCentryx Inc., a biotech company that develops drugs to treat immune system ailments, got a $50 million payday from partner and major shareholder GlaxoSmithKline PLC in August. The plan last November was to raise $57.5 million through an IPO, but with only four VC-funded health care companies successfully going public this year — and all in the first quarter — it was time for an infusion.
The Mountain View, Calif.-based company is one of several biotech… Continue Reading
Life sciences briefing: Tuesday, Feb. 5, 2008
TODAY’S HEADLINES:
Amira Pharma strikes GSK partnership on lung, heart drugs worth up to $425M (release)
Wolters Kluwer Health takes stake in Logical Images (release)
Gentiva Health acquires Home Health Care Affiliates for $55M (release)
Compuware buys Hilgraeve to upgrade healthcare IT (release)
Touchstone Health appoints Michael Muchnicki CEO (release)
Australia’s Xenome names Ian Nesbit as CEO (release)
Amira Pharma strikes GSK partnership on lung, heart drugs worth up to $425M – Amira Pharmaceuticals, a San Diego biotech focused on drugs for lung… Continue Reading
Life sciences briefing: Tuesday, Dec. 11, 2007
TODAY’S HEADLINES:
Cancer stem-cell co. OncoMed strikes GSK partnership worth up to $1.4B (release)
Kosmix pulls in $10M for health, lifestyle search (release)
CDI Bioscience pulls in $3M for protein-production improvements (release)
UroMedica takes in $7M for incontinence devices (VentureWire, sub req’d)
Draths raises $2.5M for flu drugs (PE Hub)
Cancer stem-cell co. OncoMed strikes GSK partnership worth up to $1.4B – Redwood City, Calif.-based OncoMed Pharmaceuticals, a biotech founded to target and destroy the “cancer stem cells” that researchers believe may… Continue Reading
Life sciences briefing: Wednesday, Nov. 21, 2007
Featured companies: Cerus, LabNow, Reliant Pharmaceuticals
UPDATED: Expanded items on Reliant Pharmaceuticals and Cerus.
GSK acquires Reliant Pharma for $1.65 billion — And then there were none. Reliant Pharmaceuticals, a Liberty Corner, N.J., specialty pharma that filed for an initial offering back in August, has instead decided to sell itself to GlaxoSmithKline for the eye-popping sum of $1.65 billion. The release is here. The acquisition news comes just days after doppelganger Reliant Technologies abandoned its own IPO bid (see… Continue Reading
A biotech flu vaccine and the seduction of hype
(UPDATED: See below.)
Vaccine developer Protein Sciences is all over the blogosphere today (see, for instance, items on Pharmalot and the WSJ health blog), thanks to a breathless Bloomberg piece on the little Meriden, Conn., biotech. According to Bloomberg reporter John Lauerman’s article, Protein Sciences is poised to vanquish establish flu vaccines from Big Pharma giants Novartis and GlaxoSmithKline, in an interesting case study of what happens when a quote-worthy biotech executive catches the ear of a… Continue Reading
Roundup: Guilt-free stem cells, the trials of Avandia, sponsor research bias, news from ASCO, and more
Flip switch for stem cells – Three research teams reported a technique for “reprogramming” skin cells into embryonic stem cells, those primordial bits of protoplasm that can propagate themselves indefinitely and, under the right conditions, transform themselves into any type of cell in the body. Deriving embryonic stem cells normally requires destroying an embryo — the main reason research with the cells remains limited, as does federal support for the work.
Teams from Kyoto University, MIT and… Continue Reading
Roundup: Genetic links to breast cancer, Avandia under attack, death and the drug official, and more
More genetic links for breast cancer – Whole-genome association studies that tease out links between minute genetic variations and the likelihood of disease are definitely building momentum. Over the last several days, researchers reported six new variations that increase the risk of breast cancer for women who have inherited them. (For background, see this Boston Globe piece or my recent take on the subject.) It’s now conceivable that scientists may soon have an excellent handle on… Continue Reading
Roundup: No-nukes cancer treatment, E. coli vaccines, ovarian-tissue banking, more
No nukes in lymphoma treatment – Two innovative biotech drugs that target tumor cells for destruction by tiny radioactive particles are struggling in the marketplace, in part because cancer doctors are simply too specialized to make proper use of them. The drugs — Zevalin (pictured at left), from Biogen Idec, and Bexxar, now produced by GlaxoSmithKline — consist of bioengineered antibodies that carry fragments of radioactive material directly to lymphoma tumors in the bloodstream, where the… Continue Reading
AstraZeneca ups the biotech ante
Now that AstraZeneca has made the bold — or impulsive — decision to snap up MedImmune for $15.6 billion in cash, one big question is whether the U.K. pharmaceutical giant has kicked Big Pharma’s appetite for biotech acquisitions into high gear.
The green-eyeshade types are generally still scratching their heads over the rich price, which amounted to a 21 percent premium over MedImmune’s close on Friday. The biotech was known primarily for Synagis, an antibody-based drug… Continue Reading
Biotech Roundup: Heart-disease biomarkers, drugs that go too far, “non-profit” drugs
(Note: This item has been copied over to the Life Sciences page from its original location on the VentureBeat main page. To view it in its original context, with comments, click here.)
Cautionary tales: An occasional look at events with potential long-term impact for biotechnology
Personalized medicine takes a hit — Scientists have spent more than a decade scouring the human genome to identify genetic alterations that might predict your risk of developing, say, heart trouble or cancer…. Continue Reading