Cardio drug maker Portola Pharmaceuticals takes $60M extension

San Francisco-based drug company Portola Pharmaceuticals has taken a $60 million extension to its third round of funding to see it through Phase II trials for betrixaban, a drug intended to prevent blood clots.

The company is also working on an antiplatelet agent called PRT060128. If its drugs do well in trials, the company will likely head to an IPO, as we reported alongside its last $70 million fundung.

Managing Application Performance by Understanding Applications Learn more,… Continue Reading

ImaRx: A blood-clot attacker with sinking IPO hopes

ImaRx: A blood-clot attacker with sinking IPO hopes

ImaRx, a Tuscon, Ariz., biotech developing new ways to dissolve blood clots in the lungs, lowered its IPO sights and now expects to raise no more than $17.3 million in the offering. (Its latest SEC filing is here.) Late last month, the company had hoped to raise as much as $25.9 million by pricing its shares between $6.50 and $7.50 apiece.

ImaRx now expects to price its shares at $5 apiece. That will value the… Continue Reading

Cardiovascular biotech Portola Pharmaceuticals raises $70M, eyes IPO

Portola Pharmaceuticals, a South San Francisco, Calif., biotech aiming to develop treatments for blood clots and other heart-related problems, raised $70 million in a third round of financing dominated by late-stage and public-market investors.

Among new investors in the round were Brookside Capital; AllianceBernstein; Teachers’ Private Capital, the private investment arm of Ontario Teachers’ Pension Plan; Goldman Sachs, T. Rowe Price, IBTM and CIDC. They were joined by existing investors Abingworth, Alta Partners, Advanced Technology Ventures,… Continue Reading

Portola Pharma gets $20M debt financing

Portola Pharmaceuticals, a South San Francisco biotech company developing cardiovascular and vascular disease therapies, has raised $20 million in debt financing from Hercules Technology Growth Capital.

Portola is already backed by venture firms Abingworth, Alta Partners, ATV, Frazier Healthcare Ventures, MPM Capital, Prospect Ventures and Sutter Hill Ventures.

The company said it has two drug candidates in clinical development: 1) an oral Factor Xa inhibitor in a Phase II trial for the prevention of Deep Vein Thrombosis… Continue Reading