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	<title>VentureBeat &#187; drug resistant bacteria</title>
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		<title>VentureBeat &#187; drug resistant bacteria</title>
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		<title>Life sciences briefing: Monday, Nov. 5, 2007</title>
		<link>http://venturebeat.com/2007/11/05/life-sciences-briefing-monday-nov-5-2007/</link>
		<comments>http://venturebeat.com/2007/11/05/life-sciences-briefing-monday-nov-5-2007/#comments</comments>
		<pubDate>Mon, 05 Nov 2007 17:00:39 +0000</pubDate>
		<dc:creator>David P. Hamilton</dc:creator>
				<category><![CDATA[Uncategorized]]></category>
		<category><![CDATA[antibiotics]]></category>
		<category><![CDATA[biocatalysis]]></category>
		<category><![CDATA[biotechnology]]></category>
		<category><![CDATA[deal]]></category>
		<category><![CDATA[drug resistant bacteria]]></category>

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		<description><![CDATA[<p><em><strong>Featured companies:</strong> AvidBiotics, Codexis, Imalux, Myomo</em></p>
<p><strong>UPDATED:</strong> Expanded items on AvidBiotics and Codexis.</p>
<p><strong>AvidBiotics raises $1M for anti-infective drugs &#8212; </strong>AvidBiotics, a South San Francisco, Calif., biotech developing a new generation of antibacterial proteins, raised $1 million in a first &#8230;</p><img alt="" border="0" src="http://stats.wordpress.com/b.gif?host=venturebeat.com&amp;blog=342986&amp;post=54112&amp;subd=venturebeat&amp;ref=&amp;feed=1" width="1" height="1" />]]></description>
			<content:encoded><![CDATA[<p><em><strong>Featured companies:</strong> AvidBiotics, Codexis, Imalux, Myomo</em></p>
<p><strong>UPDATED:</strong> Expanded items on AvidBiotics and Codexis.</p>
<p><a href="http://www.avidbiotics.com/"href='http://venturebeat.files.wordpress.com/2007/11/avidbiotics-logo.jpg' title='avidbiotics-logo.jpg'><img src='http://venturebeat.files.wordpress.com/2007/11/avidbiotics-logo.jpg' alt='avidbiotics-logo.jpg' /></a><strong>AvidBiotics raises $1M for anti-infective drugs &#8212; </strong><a  target="_blank">AvidBiotics</a>, a South San Francisco, Calif., biotech developing a new generation of antibacterial proteins, raised $1 million in a first funding round, <a href="http://professional.venturewire.com/story.asp?sid=NOJPQHHKQQI" target="_blank">VentureWire reports</a> (subscription required). The company didn&#8217;t disclose its investors.</p>
<p>AvidBiotics is using a new type of protein engineering to develop molecules that can successfully attack drug-resistant bacterial. That engineering system relies upon a &#8220;diversity generator&#8221; that produces a variety of modifications in protein structure that affect the molecules&#8217; ability to bind to and attack various surface molecules on bacteria. Screening the new proteins created this way allows researchers to identify the ones with the best drug-like properties. The idea is similar in certain respects to &#8220;<a href="http://en.wikipedia.org/wiki/Combinatorial_chemistry" target="_blank">combinatorial chemistry</a>,&#8221; an attempt to harness an evolution-like mechanism in the development of small-molecule drugs.</p>
<p>The company&#8217;s first target is <a href="http://www.textbookofbacteriology.net/pseudomonas.html" target="_blank">Pseudomonas aeruginosa</a>, an opportunistic bacteria that attacks immunocompromised tissues. It can cause infections of the skin, the urinary tract, the digestive system, and many other organ systems.</p>
<p><a href="http://www.codexis.com/"href='http://venturebeat.files.wordpress.com/2007/11/codexis-logo.jpg' title='codexis-logo.jpg'><img src='http://venturebeat.files.wordpress.com/2007/11/codexis-logo.jpg' alt='codexis-logo.jpg' /></a><strong>Biocatalysis firm Codexis adds $600K to recent funding &#8212; </strong><a  target="_blank">Codexis</a>, a Redwood City, Calif., developer of biocatalytic processes for manufacturing of biofuels, pharmaceuticals and other products, added $600,000 to its fourth funding round, <a href="http://professional.venturewire.com/story.asp?sid=IHHHPJIMQQI" target="_blank">VentureWire reports</a>, citing a regulatory filing. Insiders provided the funding.</p>
<p>The new funding is in addition to the company&#8217;s $37 million fourth round, which we noted <a href="http://venturebeat.com/2006/08/24/codexis-raises-37-million-in-series-d-private-financing-total-to-be-raised-up-to-40-million/">here</a>. In July, Codexis acquired Biocatalytics, an enzyme maker also focused on &#8212; you guessed it &#8212; biocatalysis. Our coverage, which goes into a little more detail about the business, is <a href="http://venturebeat.com/2007/07/19/codexis-acquires-biocatalytics-to-bolster-enzyme-manufacture/">here</a>.</p>
<p><strong>OTHER HEADLINES OF NOTE:</strong></p>
<ul>
<li> <a href="http://home.businesswire.com/portal/site/google/index.jsp?ndmViewId=news_view&amp;newsId=20071105006413&amp;newsLang=en" target="_blank">Imalux receives $2.3M grant for cancer imaging</a> <em>(release)</em></li>
<li> <a href="http://home.businesswire.com/portal/site/google/index.jsp?ndmViewId=news_view&amp;newsId=20071105006253&amp;newsLang=en" target="_blank">Medical-device maker Myomo names Thomas Glover new CEO</a> <em>(release)</em></li>
</ul>
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	<enclosure url="http://venturebeat.files.wordpress.com/2007/11/avidbiotics-logo.jpg?w=150" /><source url="http://venturebeat.com/2007/11/05/life-sciences-briefing-monday-nov-5-2007/">Life sciences briefing: Monday, Nov. 5, 2007</source>
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