VentureBeat

TODAY’S HEADLINES:

• Luminous Medical raises $24M for automated glucose monitoring (release)
• Alimera Sciences gets $30M for eye-disease drug (release)
• Vaccine maker LigoCyte draws $28M (release)
• Heartbeat tracker CardioNet trims IPO, aims for listing today (IPOhome)
• Axial Biotech takes in $6M for spinal diagnostics (release)
• Insulin bioengineer enGene receives $6.4M (release)
• GlucoLight raises funding for, well, glucose monitoring (release)
• Germany’s InflaRx gets seed funding for sepsis work (release)
• Cell imager Amnis pulls in $3.5M (VentureWire)
• Korea Bone Bank gets funding for bone transplants (release)

Luminous Medical raises $24M for automated glucose monitoring – Carlsbad, Calif.-based Luminous Medical, a medical-device maker, raised $23.5 million in a second funding round. Investors included Adams Street Partners, RiverVest Venture Partners, Finistere Ventures, De Novo Ventures and Latterell Venture Partners.

Luminous is developing an automated blood-sugar sensor for diabetic patients being treated in hospital intensive-care units and operating rooms. According to the company, keeping a tight rein on blood-glucose levels, which can soar or crash unexpectedly in diabetics, helps prevent complications while shortening hospital stays and reducing the risk of death.

Measuring such tight control, however, typically requires manually checking blood-glucose levels every 30 to 60 minutes, the company says. The Luminous device, by contrast, uses infrared spectroscopy — a technique that identifies particular molecules by measuring which wavelengths of light they absorb — to measure glucose and other blood chemicals non-invasively.

The company licensed its technology from InLight Solutions of Albuquerque, N.M., which previously invested $60 million in the technology. The device has not been approved by the FDA.

Axial Biotech takes in $6M for spinal diagnostics – Axial Biotech, a Salt Lake City diagnostic-test maker, raised $6 million as part of its second funding round. Investors included Johnson & Johnson Development, vSpring Capital and Ohio Biotech Group.

Axial, founded in 2002 by a group of spinal surgeons and geneticists, is an odd hybrid of biotech and devices. The company aims to produce tests that will predict and measure the severity of spinal problems such as scoliosis, as well as unspecified “motion-preserving technologies” — presumably an alternative to the stigmatizing back braces that orthopedists have long inflicted on children with the condition.

Insulin bioengineer enGene receives $6.4M – Canada’s enGene, a Vancouver biotech looking for ways to jump-start natural insulin production in diabetics, raised $6.4 million in a first round of funding. Investors included Saad Investments, Masa Life Science Ventures and private investors.

EnGene has an audacious — which is to say, of course, also quite chancy — approach to diabetes, in which the immune system attacks and kills insulin-producing “beta cells” in the pancreas (type 1 diabetes) or the body grows desensitized to insulin and requires higher levels (type 2 diabetes). In either case, patients often require insulin shots to maintain blood-sugar levels necessary or proper metabolism.

EnGene proposes to engineer cells in the small intestine — known as “K cells” — to produce insulin themselves. The advantage of this technique lies in the fact that K cells, like beta cells, respond to sugar levels in the gut, although they normally secrete a separate molecule. Once bioengineered to produce insulin as well, these cells could help regulate blood sugar automatically much the way beta cells normally do.

Of course, gene therapy has, in general, been a great disappointment so far, so there’s no shortage of uncertainty associated with this sort of technique. EnGene has tested its technique in mice, but not yet in humans. The startup plans to seek a second round of funding in the second half.

Alimera Sciences gets $30M for eye-disease drug – Alimera Sciences, an Alpharetta, Ga., drug developer with a focus on eye disease, raised $30 million in a third funding round. The company will now take a majority stake in its drug for diabetic macular edema, a vision-degrading complication of diabetes, which Alimera is developing with its partner pSividia.

We’ve written before about Alimera, which is presumably still contemplating an IPO this fall. All five of the company’s existing VC backers participated in the round: BA Venture Partners, Domain Associates, Intersouth Partners, Polaris Venture Partners and Venrock Associates.

Vaccine maker LigoCyte draws $28M – LigoCyte Pharmaceuticals, a Bozeman, Mont., biotech focused on new vaccines against infectious disease, raised $28 million in a third funding round. Investors included Forward Ventures, JAFCO, Novartis Venture Fund, Fidelity Biosciences, MedImmune Ventures, Athenian Venture Partners and MC Life Sciences Ventures.

The company is developing new vaccines using “virus-like particles” — usually structural viral proteins, minus the replication machinery packed in DNA or RNA — against gastroenteritis, anthrax and flu. It is also working on antibody drugs against inflammatory disease.

Many startups have tried to take on social news site Digg. Mixx is one of them, but it has a few additional features that lets users fine-tune what stories they see on the site — and it’s made some deals with big newspapers. The company has shown enough progress since launching in October that it has brought back existing investor Intersouth Partners for a $2 million round.

Similar to Digg and competitors, Mixx lets you submit stories, vote on your favorite submissions, add your own comments, and see the most popular stories on the site’s front page. It also shows you news stories, photos, videos and other submitted content based on where you live and what your self-defined interests are.

Mixx also has other differences, like its focus on user participation. Digg has an algorithm that it uses to rank the effect of a user’s vote, but reveals only limited information about the algorithm and also makes changes to it on the fly — making many top Digg users scratch their heads (our coverage). In contrast, Mixx employees themselves blog regularly and openly explain how users can accumulate points for doing things like submitting popular stories and leaving quality comments — and even gain access to special powers (example).

For a different approach to customization, take a look at Reddit. Possibly the most successful Digg competitor, this Conde Naste-owned company also offers a white-label social news services that is gaining some traction among users. For example, there’s one version of Reddit called l33t — or “elite tech news” — that features the submissions, votes and comments of a core group of bloggers and their friends.

Every social news startup seems to be looking towards print publications. Digg itself has a deal with the Wall Street Journal.

Mixx, a product of a McLean, Va. company called Recommended Reading, has been favored by newspapers looking to boost their web sites with a custom social news site focused on their articles. It raised a small amount of funding from one client, the LA Times, last fall (our coverage). It also has deals with USA Today, Reuters.com, The Weather Channel, and others.

The company previously raised $1.5 million round of funding, in a round led by Intersouth Partners.

Screenshot:

TODAY’S HEADLINES:

• PEAK Surgical takes in $21M for electrosurgical tools (release)
• CellGate acquired by Australian cancer biotech ProGen for $2.5M (release)
• Traversa raises $2M for RNAi-delivery technologies (release)
• RemitDATA, Web-based healthcare-service co., takes in $5.5M (bizjournals.com)
• Spinal-implant maker Archus Orthopedics gets $10M venture loan (release)
• Promedior pulls down another $5.5M for fibrotic disease (release)
• Acrongenomics takes 11 percent stake in Molecular Vision (release)
• Hepatitis drug-developer Biolex withdraws IPO (IPO Home)
• Employee drug screener eScreen gets Carlyle investment (release)
• NovaMin raises $2.5M for dental-care products (VentureWire)
• Cardious receives $1.5M for heart-valve repair (VW)
• PE-backed Spire Healthcare buys PE-backed Classic Hospitals for £145M (FT)
• Aberdare Ventures promotes two principals to partner (release)

CellGate acquired by Australian cancer biotech ProGen for $2.5M –CellGate, a Redwood City, Calif., biotech working on new cancer drugs, sold itself to ProGen, an Australian biotech also focused on cancer, for the equivalent of about $2.5 million. The release is here. Needless to say, this represents a fire sale for a biotech that seems to have run out of time.

CellGate was pursuing drugs that aimed to shut down the growth of cancer cells either by inhibiting polyamine or by “turning down” the activity of cancer-related genes. ProGen will conduct an 18-month assessment of CellGate’s first drug candidate, a polyamine inhibitor that had already completed an early stage, phase I clinical trial, before deciding upon a mid-stage, phase II program. ProGen will also evaluate a stable of CellGate’s preclinical drug candidates.

ProGen will issue shares worth $1.5 million for CellGate’s assets, and will assume net liabilities of roughly another $1 million. The sale represents a significant loss for CellGate’s investors, including Healthcare ventures and New Enterprise Associates, who as recently as 2002 put $10 million into the company in a fourth funding round. I haven’t been able to piece together how much CellGate raised over its lifetime, although it’s certainly considerably more than that $10 million.

Traversa raises $2M for RNAi-delivery technologies – Traversa Therapeutics, a La Jolla, Calif., biotech working on ways to deliver RNA-based drugs to their cellular targets, raised $2 million in a first financing round. Investors included San Diego Tech Coast Angels, Mesa Verde Venture Partners and Morningside Group.

Traversa’s work is intimately involved with RNA interference, a newly discovered technique for “silencing” disease-related genes using short strands of RNA that trigger a natural cellular mechanism for shutting down genes. Getting those short RNA molecules into cells in the first place, however, isn’t particularly easy.

Traversa claims to have solved that problem, although it doesn’t appear to be saying how. The company will license its RNA-delivery approach to drug companies, and also offers it for use as a drug-screening technology.

RemitDATA, Web-based healthcare-service co., takes in $5M – Memphis, Tenn.-based RemitDATA, a provider of Web-based healthcare-data services, raised $5 million in a new funding round.Noro-Moseley Partners and SSM Partners provided the funding.

RemitDATA offers Web-based tools for individual physician practices designed to help them track insurance and Medicare reimbursements and scan paper records into digital form. The company also makes a sales-management tool for the homecare industry.

Promedior pulls down another $5.5M for fibrotic disease – Promedior, a Malvern, Pa., biotech focused on fibrotic disease, raised an additional $5.5 million as an extension to its first funding round. Polaris Venture Partners, Morgenthaler Ventures, HealthCare Ventures and Easton Capital participated in the financing.

Fibrotic disease is a general name for conditions that entail repeated bouts of inflammation followed by scarring that, over time, can lead to organ failure. Examples include heart failure, cirrhosis and kidney failure. Promedior aims to develop drugs that can slow or reverse the scarring process, and intends to begin clinical trials of its first drug candidate this year. The company previously raised $7 million in its first funding round.

Acrongenomics takes 11 percent stake in Molecular Vision – Acrongenomics, a Swiss company that acquires and develops life-sciences technology, took a 10.5 percent stake in Molecular Vision, a developer of credit-card sized diagnostic devices. Acrongenomics had previously announced its intent to acquire Molecular Vision, so presumably this is the first step in that plan. The release is here.

Hepatitis drug-developer Biolex withdraws IPO – Biolex Therapeutics, a Pittsboro, N.C., biotech developing ways to manufacture protein drugs in an aquatic-plant system, withdrew its planned $70 million IPO. We previously covered Biolex and its IPO dreams here.

NovaMin raises $2.5M for dental-care products – NovaMin, an Alachua, Fla., company working on tooth-remineralization products, raised $2.5 million in a third round of funding and expects another $2.5 million, VentureWire reports. Intersouth Partners provided the financing.

Cardious aims at $1.5M for heart-valve repair – Cardious, a Northfield, Minn., medical-device company working on a heart-valve bypass device, is raising $1.5 million in a first funding round, VentureWire reports. The company aims to raise the funds from angel investors. Cardious is developing an aortic-valve replacement that can be put in place on a beating heart, rerouting blood flow around the damaged valve.

TODAY’S HEADLINES:

• AcryMed, wound-healing specialist, sells itself to I-Flow for $25M (release)
• Stent maker Devax pulls $85M IPO filing (Edgar)
• Cempra Pharma gets $10M for anti-infective drugs (TechJournal South)
• Genesis Genomics takes in C$312K for DNA-based diagnostics (GenomeWeb)

AcryMed, wound-healing specialist, sells itself to I-Flow for $25M — AcryMed, a Beaverton, Ore., device maker focused on bleeding control and wound healing, agreed to sell itself to I-Flow, a publicly traded maker of drug-delivery systems, for $25 million in cash. The release is here.

AcryMed currently markets several types of wound dressings that use ionic silver — which apparently has antimicrobial properties — to prevent infection and “microlattices” to promote healing. AcryMed has also developed a technique for depositing silver particles on the surface of medical devices to prevent bacterial contamination. I-Flow says it expects the company’s technology to assist in developing new antimicrobial catheters and silver-based transparent wound dressings.

Cempra Pharma gets $10M for anti-infective drugs — Cempra Pharmaceuticals, a Research Triangle Park, N.C., specialty pharma focused on new drugs for overcoming antibiotic resistance, raised $10 million in a second funding round. Investors included Aisling Capital, Intersouth Partners, Optimer Pharmaceuticals and banker I. Wistar Morris.

That round is apparently still open, as PE Hub sourced its report to a regulatory filing. Cempra appears to have licensed its antibiotic candidates and its technology platform from Optimer Pharmaceuticals, with whom it concluded a deal in April 2006.

Featured companies: Abiant, CellXplore, Diffusion Pharmaceuticals, WMR Biomedical, Zosano Pharmaceuticals

Diffusion Pharma raises $4.5M for vascular-disease and brain-cancer drug — Charlottesville, Va.-based Diffusion Pharmaceuticals, a biotech focused on drugs that enhance oxygen diffusion, raised $4.5 million in a private placement. Angel investors provided the funding, which brings Diffusion’s take to $10.2 million in equity and $2.6 million in government R&D grants.

Diffusion’s lead drug candidate — trans sodium crocetinate, or TSC — is designed to increase oxygen levels in otherwise oxygen-starved tissues. The drug just completed an early-stage clinical trial for safety, and will move on to mid-stage trials in two conditions: peripheral vascular disease and brain cancer.

Abiant draws $600K for advanced bio-imaging — Chicago’s Abiant, a device company now developing image-processing methods and software to speed the process of drug development, raised $600,000 in a private placement. Heartland Angels, Kettering Medical Center, and other investors provided the funding.

CellXplore raises $500,000 for breast-cancer diagnostics — CellXplore, a New Brunswick, N.J., biotech working on blood proteins that indicate early signs of cancer, raised $500,000 in new funding. Foundation Venture Capital Group provided the cash. The company has identified several “biomarkers” found in blood that it believes may not only identify the disease, but help oncologists assess different types and stages of cancer.

Heart- and eye-device maker WMR Biomedical assembles $13.1M — Cambridge, Mass.-based WMR Biomedical (no Web site, apparently), a developer of medical devices for cardiology and ophthalmology, raised $13.1 million in a second funding round, PE Hub reports, citing a regulatory filing. Investors included Intersouth Partners, North Bridge Venture Partners and Polaris Venture Partners. Although WMR remains largely tight-lipped about its intentions, this page on the Massachusetts Biotechnology Industry Directory site suggests it has a pretty illustrious scientific pedigree, as its founders include Harvard chemist George Whitesides and MIT’s Bob Langer.

Macroflux changes name to Zosano Pharma — There isn’t a whole lot more to say about this, actually, although the company put out a full release about it. Zosano is based in Fremont, Calif., and develops needle-free “transdermal” patches that use drug-coated “microprojections” — each about 200 microns long — to penetrate the outer layer of skin. Since the main difference between a microprojection and a needle seems to be whether the pointy object actually injects a drug or not — something of an academic distinction to anyone on the receiving end, I suspect — it’s not entirely clear to me what sort of advantage this system may have over competing needle-free approaches, such as that of Stratagent, which recently merged with Corium (our coverage in the first item here).

Featured companies: Aldagen, LDR, Lyten Endoscopy, MachLabs, Permatox, TeleMedicine Clinic, ThromboVision

Spinal-implant maker LDR raises $25M — Austin, Texas-based LDR, a maker of spinal implants, raised $25 million in a third funding round. Investors included Telegraph Hill Partners, Austin Ventures, Rothschild Private Equity and PTV Sciences.

LDR sells spinal-fusion devices, artificial disks and other spine-related devices in more than 30 countries, and plans to use the funds for further expansion.

Aldagen adds $9M for adult stem-cell work — Aldagen, a Durham, N.C., biotech developing regenerative therapies with “adult” stem cells, raised an additional $9 million (PDF link), bringing its third funding round to a total of $23 million. Investors in the additional financing include Tullis-Dickerson, CNF Investments, Harbert Venture Partners and Intersouth Partners.

The company’s most advanced experimental treatment uses stem cells derived from umbilical-cord blood to somehow improve the speed and effectiveness of cord-blood transplants in children, although the company doesn’t explain how. Nor has it revealed the results of an early-stage human test. Other treatments now entering clinical trials use stem or related progenitor cells isolated from a patient’s own bone marrow to treat heart failure or clot-related oxygen deprivation in the limbs.

The Triangle Business Journal has more.

ThromboVision raises $4M for personalized-medicine diagnostics — The Houston, Texas, biotech ThromboVision said it raised $4 million in a first funding round. Investors included the private-equity firm National Healthcare Services and private investors.

ThromboVision is developing new tests of platelet activity that may help doctors determine which patients are most likely to respond to low doses of blood thinners such as aspirin or Plavix, which are used to prevent clots that can cause heart attacks or strokes. This is similar — in concept, at least — to the FDA’s recent push to require the use of genomic tests to determine the proper dosing of warfarin, another blood thinner. (See our coverage here.)

MachLabs launches two device companies — MachLabs, a Redwood City, Calif., investor partnership founded by entrepreneurs Michael Laufer and John Lonergan, recently launched two medical-device startups, VentureWire reports (subscription required). Lyten is developing a minimally invasive treatment for obesity, while Permatox hopes to introduce a non-invasive alternative to Botox.

TeleMedicine Clinic receives €7M for radiology services — Barcelona-based TeleMedicine Clinic, a center for the outsourced analysis of medical images such as X-rays and MRIs, raised €7 million ($9.7 million), VentureWire reports. Investors included Kennet Partners, Active Capital Partners and an undisclosed European seed investor.

Featured companies: Cyntellect, Lectus Therapeutics, NeoMatrix, Nexstim, Pearl Therapeutics, Proteon Therapeutics, SupplyScape

(UPDATED at 10am PT: See below.)

Airway-disease specialist Pearl Therapeutics raises $15.5M — Redwood City, Calif.-based Pearl Therapeutics, a drug-formulation company focused on respiratory disease, raised $15.5 million in a first funding round. Investors included New Leaf Ventures, Clarus Ventures and 5AM Ventures.

Pearl doesn’t appear to have a working Web site yet, but according to its release, the company aims to treat unspecified airway diseases using “particle technologies” it has licensed from Nektar Therapeutics. Nektar, of course, is the company that spent years co-developing the inhalable insulin Exubera with Pfizer, only to see it flop in the marketplace — not least because the bulky inhaler resembled nothing so much as a bong.

In fact, Pearl’s ties to Nektar run deep. In addition to licensing its basic technology from Nektar, the company was founded in 2006 by two former Nektar executives, Adrian Smith and Sarvajna Dwivedi. Pearl most likely also aims to reformulate existing drugs into a better inhalable form — and presumably hopes for better luck in doing so.

Proteon Therapeutics sucks in $12M for vascular drug — Proteon, a Waltham, Mass., biotech, raised $12 million in a follow-on to its first funding round. Investors included TVM Capital, Skyline Ventures, Prism VentureWorks and Intersouth Partners.

Proteon’s main drug candidate, PRT-201, aims to do something new by permanently enlarging blood vessels at the site of administration. The technology is based on elastases, a type of protein-cutting enzyme, which supposedly modify the “extracellular matrix” of blood vessels in order to enlarge them. The company expects the drug might be useful for kidney-dialysis patients, who now often have to undergo surgery to create blood vessels large enough for a connection to the blood-filtration devices, and in peripheral arterial disease.

Brain scanner Nexstim beams in €8M — Nexstim , a Helsinki, Finland-based developer of brain-imaging techniques, raised €8 million ($10.9 million) in a private placement. Investors included HealthCap, LSP (Life Sciences Partners), Finnish Industry Investment and Sitra.

Nexstim is working on a new brain-imaging technique it calls “navigated brain stimulation.” The details are pretty hairy — check out the company’s release if you’d like to know more — but it essentially combines several different electromagnetic-imaging techniques with a movable coil that can be guided wherever the operator would like. The system isn’t approved for clinical use, although Nexstim said the funding would allow it to obtain the necessary regulatory approval.

Health software company SupplyScape raises $10M, names new CEO — SupplyScape, a Woburn, Mass., developer of supply-chain software for life-sciences companies, raised $10 million in a third funding round. Investors in the latest round included IDG Ventures Boston, North Bridge Venture Partners, Pilot House Ventures, Bethesda Partners, and Pfizer Strategic Investments Group.

The company also named Mark O’Connell, former CEO of MatrixOne, as its chief executive.

The average person, however, could be forgiven for having no clue what SupplyScape actually does. According to the company’s press releases, it makes software to “maximize product integrity and create business value for pharmaceutical, biotech, medical device companies.” Its Web site promises “collaborative pharmaceutical value chains” that improve “security and profitability.” As it turns out, the company’s software helps track and trace drugs from their point of manufacture through various distribution channels in order to guard against counterfeits, at least so far as I can tell from its Web site.

Cancer screener NeoMatrix raises $9.6M — San Diego’s NeoMatrix, a company focused on early detection of breast cancer, raised $9.6 million in a third funding round. Private investors provided the funding, the company told me. (Its release doesn’t include these details.) Out of sheer coincidence, two southern California businessmen — Anthony Ciabattoni and Richard Franco Sr. — also just joined the company’s board (see the release for details).

Founded in 2000, NeoMatrix sells a screening test that detects pre-malignant or malignant cells in “nipple aspirate fluid,” which is extracted from the breast using a “gentle” suction device. The company said the new funds will allow it to hire its first sales reps, expand its marketing efforts and to convert or retire remaining debt the company used to finance development of its test.

Lectus draws in £3M for MS drugs — Cambridge, England-based Lectus Therapeutics, a biotech focused on a class of drugs known as ion-channel modulators, raised £3 million ($6.1 million) in funding from the Wellcome Trust. The investment is intended specifically to fund development of drugs for multiple sclerosis. Lectus had previously identified its primary disease interests as urinary bladder disorders, pain and angina.

Cell imager Cyntellect adds $3M in funding — Cytellect, a San Diego developer of cell imaging and manipulation systems, raised an additional $3 million in a fourth funding round, bringing the total for the round to $18.1 million. Bru II Venture Capital Fund, based in Reykjavik, Iceland, provided the additional funding.

Cyntellect’s laser-based equipment makes it possible to fluorescently image cells, isolate and destroy unwanted cells in a sample, and to “optoinject” various molecules directly into cells. See our previous coverage here.

UPDATE (10am PT): Added items on Cyntellect, Lectus Therapeutics, NeoMatrix, Nexstim, Pearl Therapeutics, and Proteon Therapeutics.

Although I try to stay on top of events in the life sciences, announcements do sometimes manage to slip through the cracks. Some days, in fact, I end up triaging. Because the roots of this site — not to mention many of its readers — are in Silicon Valley, Bay Area events are a priority. Then come announcements from the rest of the U.S., then Asia, then Europe. Also, smaller or partial fundings tend to take a backseat.

Looking back over my notes — it’s the only way I keep anything straight — I see quite a few of these orphans have piled up. So for the sake of completeness, I’m inaugurating this occasional feature to recap the fundings, mergers and IPOs that got away from me. I’ll put all the details below the fold, so only forge ahead if you’re really interested. RSS subscribers, unfortunately, are going to get the whole thing anyway.

Read the rest of this entry »

Argolyn Bioscience, a Charleston, S.C.-based developer of drugs for neurological problems, raised $15.8 million in a first financing round. The funding was led by Intersouth Partners and Quaker BioVentures, joined by Amgen Ventures.

Argolyn is at work on new peptide-based drugs, which are made from short stretches of protein, for schizophrenia and pain. Neither of its lead candidates have yet entered clinical trials, although the company said the new funding will allow it to begin human tests. Peptides are theoretically much more selective than traditional “small molecule” drugs, but usually can’t be administered in pill form because their fragile molecules break down in the digestive system. Argolyn says it can modify peptides to improve their stability, although it so far stops short of saying it can deliver them orally.

Research Triangle Park, N.C.-based Viamet raised $4 million in a first round of funding. The round was co-led by Hatteras Venture Partners and Intersouth Partners.

Viamet is developing drugs that target metalloenzymes — a diverse group of catalyst molecules that include metal atoms — in infectious disease, inflammation and cancer. The company was founded in 2005.

Biolex Therapeutics, a Pittsboro, N.C., developer of technology for improving the properties of monoclonal antibodies, raised $30 million in a third funding round.

Biolex specializes in producing proteins that are difficult to make with existing bioengineering processes and in optimizing the biological properties of monoclonal antibodies. It is also pursuing its own experimental drug candidates, and said the proceeds of this round will serve primarily to advance Locteron, an experimental time-release form of interferon alfa, into late-stage human tests against hepatitis C.

Investor Growth Capital led the round, joined by two other new investors, JP Morgan Securities and Easton Capital. Existing shareholders including Quaker BioVentures, Polaris Venture Partners, Intersouth Partners, Mitsui & Co. Venture Partners, Johnson & Johnson Development Corporation and Dow Venture Capital also participated. The company’s release is here (PDF).