Trinity Biosystems raises $7.5M bridge to treat endocrine disorders

Trinity Biosystems, maker of a drug that can treat certain endocrine disorders, has brought in $7.5 million in bridge funding from Amgen Ventures, Life Science Partners, Lilly Ventures, Sanderling Ventures and SR One, according to Dow Jones VentureWire. Based in Menlo Park, Calif., the company has raised about $33.75 million since its first round of financing in 2004.

Sans IPO, Bayhill secures $350M in Genentech licensing deal

Months after giving up on its IPO hopes last year — when the market was especially brutal for lifescience companies — Bayhill Therapeutics has landed a licensing deal worth $25 million in upfront cash and equity with Genentech. It could bring in as much as $325 million more if it hits certain sales and regulatory milestones, joining the ranks of several biotech firms that ditched public offerings for lucrative equity deals, VentureWire reports (citing Elixir… Continue Reading

Intradigm closes $21.4M for cancer therapeutics

Biotech firm Intradigm has tacked an additional $2.9 million onto its second round of funding, bringing its total to $21.4 million. The new money will be used to advance its RNA interference-based line of therapeutics used to treat cancer.

The Palo Alto, Calif.-based company says it distinguishes itself from others pursuing RNA interference strategies by also offering technology to deliver treatment to very specific locations within the body.

Astellas Venture Management led this most recent tranche, which… Continue Reading

Intradigm lands $18.5M to advance oncology treatment

Intradigm, a biotech company that develops RNA interference treatments for cancer, announced today that it took $18.5 million in a second round of financing that included new investors Lilly Ventures, Roche Venture Fund, MP Healthcare Venture Management, and existing investors Alta Partners, Frazier Healthcare Ventures, MediBic Alliance Technology Fund and Novartis Venture Fund.

The Palo Alto, Calif.-based company has developed an RNA interference therapy for cancer, as well as a mode for delivering it to the… Continue Reading

Life sciences briefing: Thursday, Nov. 1, 2007

Life sciences briefing: Thursday, Nov. 1, 2007

Featured companies: Asteres, HemaQuest Pharmaceuticals, Nanosphere, Novalar Pharmaceuticals, Tranzyme Pharma

(UPDATED: Expanded items for Nanosphere, HemaQuest and Transzyme. Moved Novalar to a separate item here.)

Diagnostic maker Nanosphere prices IPO at low end of range, raises up to $113M — Nanosphere, a Northbrook, Ill., biotech focused on nanotech-derived diagnostics, priced its IPO at $14 a share, at the low end of its estimated range. The company, which could sell as many as eight million shares, stands to raise up… Continue Reading

Life sciences briefing: Wednesday, Sept. 26, 2007

Life sciences briefing: Wednesday, Sept. 26, 2007

Featured companies: Ablynx, Cardiosolutions, Carigent Thereapeutics, Elusys, Genome Corp., GlobeImmune, Novazone, Targanta Therapeutics, Waterfront Media

UPDATED at 5:45am on 9/27/07

GlobeImmune raises $41M for immune-system therapies — GlobeImmune, a Louisville, Colo., biotech focused on new forms of immunotherapy to treat viral infections and cancer, raised $41.2 million in a third funding round. Investors included Wexford Capital, Celgene, the Mellon Family Investment Company, the Richard King Mellon Foundation, Eminent Venture Capital, Boston Life Science Venture, WRF Capital, HealthCare Ventures,… Continue Reading

Life sciences briefing: Wednesday, Aug. 29, 2007

Life sciences briefing: Wednesday, Aug. 29, 2007

(UPDATED at 3:10pm PT: See below.)

Featured companies: Agendia, EndoGastric Solutions, FlowCo, Gentris, MedManage Systems, ParagonDx, Presidio Pharmaceuticals, Xoova

Presidio Pharma raises $26M for viral treatments — San Francisco’s Presidio Pharmaceuticals, a biotech developing new antiviral drugs, raised $26 million in a second funding round. Investors included Panorama Capital, Baker Brothers Investments, Bay City Capital, Ventures West Capital, Nexus Medical Partners, Sagamore Bioventures, George Rathmann Fund and Peninsula Overview Partners.

Presidio’s lead drug candidates take aim at HIV, hepatitis… Continue Reading

Funding roundup: Announcements that got away

Funding roundup: Announcements that got away

Although I try to stay on top of events in the life sciences, announcements do sometimes manage to slip through the cracks. Some days, in fact, I end up triaging. Because the roots of this site — not to mention many of its readers — are in Silicon Valley, Bay Area events are a priority. Then come announcements from the rest of the U.S., then Asia, then Europe. Also, smaller or partial fundings tend to… Continue Reading

BioVeda China gets $10M from Eli Lilly venture fund

BioVeda China, an international VC fund focused on life science in China, raised $10 million from Lilly Asian Ventures, a spinoff of the Eli Lilly venture arm Lilly Ventures. The funds will be invested in local Chinese life-science companies.

From the BioVeda press release:

For the past 12 months, BioVeda China has led a total of more than US$120 Million financing for six companies. In addition, BioVeda provides strategic assistance to its portfolio companies to power their… Continue Reading

Avid Radiopharmaceuticals, maker of imaging reagents, raises $26M for clinical trials

Avid Radiopharmaceuticals, a Philadelphia-based maker of “molecular imaging agents” that help highlight diseased tissue in various medical scans, raised $26 million in a third round to develop early-detection products for Alzheimer’s and Parkinson’s disease.

AllianceBernstein and Safeguard Scientifics led the round. Previous investors including Pfizer Strategic Investments Group, the venture arm of Pfizer; Lilly Ventures, the venture arm of Eli Lilly; RK Venture Group; and BioAdvance also joined the round.

Avid’s development efforts are focused on new… Continue Reading