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Posts Tagged ‘inv:Signet-Healthcare-Partners’

peak-surgical-logo-200px.gifPalo Alto, Calif.-based PEAK Surgical, a device company developing new surgical tools that aim to control bleeding via electric energy, raised $21 million in a third funding round. Investors included Signet Healthcare Partners, Lehman Brothers and Venrock Associates.

The company is working on new electrosurgical tools that it says should offer significant improvements over the existing technology for using electric pulses to heat surgical instruments for cutting or coagulation of tissue. PEAK doesn’t go into great detail about its technique on its Web site or in its release, except to cite a number of scientific references and to say that it relies on short-pulsed, “plasma-mediated” electrical discharges.

The technology, however, originated at Stanford, where PEAK, it turns out, stands for “pulsed electron-avalanche knife.” The technique, developed by a team led by Daniel Palanker, involves using a high voltage electric field to create a plasma, a kind of electrically charged gas, which can be shaped and controlled to make clean cuts in tissue.

PEAK — the company, that is — claims the technology can limit the heat damage that normal electrosurgical tools can cause to surrounding tissue. Although the technique seems to have originated for use in retinal surgery, PEAK says that it is exploring its use in almost every surgical field but ophthalmic, including general, heart, gynecologic, plastic and neurological surgery.

Featured companies: Alpex Pharma, Applied Computational Technologies, Separation Design Group, ThermalTherapeutics Systems

alpex-pharma-logo.jpgSwitzerland’s Alpex Pharma raises $9M for plop, plop, fizz, fizz drugs– Alpex Pharma, a Mezzovico, Switzerland drug-formulation company, raised $9 million (CHF 10.9 million) in a second round of funding. Investors included BB Biotech Ventures and Signet Healthcare Partners.

The company essentially reformulates pharmaceuticals for other companies with technologies that make pills melt quickly, allowing them to be taken without water, or to “effervesce” — that is, dissolve — in liquid, much like Alka-Seltzer. Founded in 1988 under the name Aesculapius Pharma, Alpex was acquired by Elan Pharmaceuticals in 1992. Private-equity funds controlled by Sanders Morris Harris then acquired a majority interest in 2004 and changed the company’s name to Alpex.

plsg-logo.jpgPittsburgh Life Sciences Greenhouse invests $450K in three firms — The Pittsburgh Life Sciences Greenhouse, which we last covered in the sixth item in this daily briefing, has struck again, funding three local companies to the tune of $450,000. The public-private partnership invested $200,000 in ThermalTherapeutics Systems, which is working on a more efficient pump for chemotherapy drugs. Applied Computational Technologies received a $150,000 investment for development of a radiation-dose calculation engine. Medical-oxygen concentrator Separation Design Group received $100,000.

splitrock-logo.jpgSplit Rock Partners names Jagi Gill entrepreneur-in-residence — Split Rock Partners, a VC firm with offices in Minneapolis and Menlo Park, Calif., made medical-device executive Jagi Gill an entrepreneur-in-residence. Gill, currently chairman of PhysioStream and the former CEO of Sage Medical Technologies, will aim to seed new medical-device companies for the firm.

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