Life sciences briefing: Friday, Nov. 30, 2007

Life sciences briefing: Friday, Nov. 30, 2007

Featured companies: Fate Therapeutics, Medgenics, Satoris

UPDATED: Expanded items on Fate Therapeutics and Medgenics. The Satoris item is now a standalone post here.

Fate Therapeutics launches regenerative-medicine quest with $12M — In one of the splashiest launches in recent memory, Seattle’s Fate Therapeutics launched a new regenerative-medicine quest and… Continue Reading

Healthcare IT co. MedAssets sets IPO range, aims for $221M

Healthcare IT co. MedAssets sets IPO range, aims for $221M

MedAssets, an Alpharetta, Ga., provider of IT and services designed to maximize hospital revenue, said it plans to sell as many as 13.8 million shares at a price of $14 to $16 apiece, for a maximum IPO take of $221 million. The company’s latest SEC… Continue Reading

IPO roundup: Broncus Tech aims to breathe in $86M, Aegerion Pharma rides again, and more

IPO roundup: Broncus Tech aims to breathe in $86M, Aegerion Pharma rides again, and more

Broncus Tech, medical device maker, files for $86M IPO — Broncus Technologies, a Mountain View, Calif., developer of minimally invasive devices for treating emphysema, filed to raise $86 million in an initial offering. The company’s SEC filing is here.

The Broncus technology is a minimally invasive,… Continue Reading

Life sciences briefing: Thursday, Nov. 15, 2007

Life sciences briefing: Thursday, Nov. 15, 2007

Featured companies: BioVex, FullTurn Media, Humanetics, N Spine, Novitas Capital, Reliant Technologies, Symbios, Vaxart, Virtual Radiologic, Winston Laboratories, Zosano Pharma

EXPANDING ITEMS: Stay tuned.

Vaxart receives $3.3M for oral vaccines — San Francisco’s Vaxart, a biotech developing novel adenovirus-based vaccines, raised $2.7 million in a first funding round. Vaxart… Continue Reading

EnteroMedics and its risky obesity device, the latest victims of the IPO haircut

EnteroMedics and its risky obesity device, the latest victims of the IPO haircut

(UPDATED: See below.)

(NOTE: This item was originally published as part of today’s life-sciences briefing.)

EnteroMedics, a St. Paul, Minn., device maker working on a neuromodulation implant for treating obesity, slashed its expected IPO pricing by half, lowering it to a range of $8 to $9 instead of… Continue Reading

Life sciences briefing: Wednesday, Nov. 14, 2007

Life sciences briefing: Wednesday, Nov. 14, 2007

Featured companies: Advanced Bio-Surfaces, Ambit Biosciences, EnteroMedics, Molecular Vision, Skyline Ventures

UPDATED: Expanded items on Skyline Ventures, Ambit, and Molecular Vision, and moved EnteroMedics to a new item here.

Skyline Ventures raises $350M life-sciences fund — Skyline Ventures, a Palo Alto, Calif., VC firm, closed a $350 million fund… Continue Reading

IPOs: Biotech ChemoCentryx and specialty-pharma Xanodyne head for the public market

IPOs: Biotech ChemoCentryx and specialty-pharma Xanodyne head for the public market

ChemoCentryx files for $58M IPO to fund autoimmune, inflammation drug — Mountain View, Calif.-based ChemoCentryx, a biotech focused on new small-molecule drugs that affect a class of biochemical signals known as chemokines, filed to raise $57.5 million in an initial offering. The company’s SEC filing… Continue Reading

Life sciences briefing: Monday, Nov. 12, 2007

Life sciences briefing: Monday, Nov. 12, 2007

(UPDATED: See below.)

Featured companies: Anaptys Biosciences, Arterial Remodeling Technologies, Cambria Biosciences, CaseNet, ChemoCentryx, Ensemble Discovery, MediQuest, Piedmont Pharmaceuticals, Raven Biotechnologies, Sensys Medical, Verus Pharmaceuticals, Xanodyne Pharmaceuticals

UPDATED: Expanded items on Anaptys, Arterial Remodeling, Raven Biotech, Sensys and MediQuest. Moved ChemoCentryx and Xanodyne to a separate item.

Antibody-drug maker Raven Biotech… Continue Reading

Life sciences briefing: Wednesday, Nov. 7, 2007

Life sciences briefing: Wednesday, Nov. 7, 2007

Featured companies: Aryx Therapeutics, BioForm Medical, Health Market Science, Hypobaric Therapeutics, Mobile Medical International

UPDATED: Expanded items on BioForm, Aryx, Hypobaric and Mobile Medical.

Medical aethetics co. BioForm Medical prices IPO below range, raises up to $92M — BioForm Medical, a wrinkle-treatment maker based in San Mateo, Calif., priced… Continue Reading

Life sciences briefing: Thursday, Nov. 1, 2007

Life sciences briefing: Thursday, Nov. 1, 2007

Featured companies: Asteres, HemaQuest Pharmaceuticals, Nanosphere, Novalar Pharmaceuticals, Tranzyme Pharma

(UPDATED: Expanded items for Nanosphere, HemaQuest and Transzyme. Moved Novalar to a separate item here.)

Diagnostic maker Nanosphere prices IPO at low end of range, raises up to $113M — Nanosphere, a Northbrook, Ill., biotech focused on nanotech-derived diagnostics,… Continue Reading

Life sciences briefing: Wednesday, Oct. 31, 2007

Life sciences briefing: Wednesday, Oct. 31, 2007

Featured companies: AerovectRx, Dicerna Pharmaceuticals, Harmony Information Systems, Intelligent Hospital Systems, Merrion Pharmaceuticals, Syntaxin, SymBio Pharmaceuticals

UPDATED: Expanded items on Harmony Info, SymBio Pharma and Merrion Pharma, added Dicerna item.
UPDATE REDUX: Added Syntaxin item.

U.K. biotech Syntaxin raises £16M for pain and nervous-system drugs — Syntaxin, a U.K. biotech focused… Continue Reading

Life sciences briefing: Tuesday, Oct. 30, 2007

Life sciences briefing: Tuesday, Oct. 30, 2007

Featured companies: Acceleron Pharma, Bledsoe Brace Systems, Eurobiobiz, Genoptix, Harmony Information Systems, ImmuneWorks, Pasteuria Bioscience, Renal CarePartners, Quantum Genomics, Synergy Software, Vitreo Retinal Technology

UPDATED: Expanded items on Genoptix and Acceleron Pharma.

Diagnostics biotech Genoptix prices IPO above range, raises up to $98M — Genoptix became one of the… Continue Reading

IPO roundup: Bioheart, Merrion Pharma in limbo; Reliant vs. Reliant road shows; upcoming offerings

IPO roundup: Bioheart, Merrion Pharma in limbo; Reliant vs. Reliant road shows; upcoming offerings

Bioheart’s IPO-related chest pains continue — The week of Oct. 22 has come and gone, and there’s no sign of the scheduled — and already battered — IPO of Bioheart, the Florida company that hopes to treat damaged hearts with patients’ own muscle stem cells…. Continue Reading

Life sciences briefing: Friday, Oct. 26, 2007

Life sciences briefing: Friday, Oct. 26, 2007

Featured companies: Allozyne, Arteriocyte Medical Systems, Arthrosurface, Bay City Capital, EnteroMedics, OncoVista, Novotech, Power Medical Interventions, Reliant Technologies

UPDATED: Expanded items on Allozyne, Reliant Tech, Power Medical and Bay City Capital.
UPDATE REDUX: Added item on EnteroMedics IPO.

Seattle’s Allozyne draws $30M for new interferon — Allozyne, a Seattle biotech… Continue Reading

XDx marks a spot: An $86M IPO for gene-expression diagnostics

XDx marks a spot: An $86M IPO for gene-expression diagnostics

(UPDATED: See below.)

When XDx yesterday filed to raise up to $86.3 million in an IPO, the Brisbane, Calif., company joined just a handful of similar molecular-diagnostic companies to test the public markets. XDx specializes in a new type of diagnostic test that measures gene activity —… Continue Reading

Life sciences briefing: Wednesday, Oct. 24, 2007

Life sciences briefing: Wednesday, Oct. 24, 2007

Featured companies: Angstrom Medica, Asuragen, Aryx Therapeutics, HistoRx, MiMedx, Pioneer Surgical, Transfusion & Transplantation Technologies, Tolerx, Vivo Ventures

UPDATED: Expanded Aryx and XDx items.
UPDATE REDUX: Expanded Tolerx item, moved XDx to a separate post.

Aryx sets IPO range, seeks $92M for redesigned drugs — Fremont, Calif.-based Aryx Pharmaceuticals,… Continue Reading

Life sciences briefing: Tuesday, Oct. 23, 2007

Life sciences briefing: Tuesday, Oct. 23, 2007

Featured companies: Apex Radiology, Arcxis Biotechnologies, EKR Therapeutics, Franklin & Seidelmann, Michelson Diagnostics, SensiGen, Vascular Closure Systems

UPDATED: Expanded items on Arcxis, Vascular Closure and Archemix.

Arcxis pulls in $2M for DNA tools — Arcxis Biotechnologies, a Pleasanton, Calif., biotech tool maker focused on analysis of DNA and proteins… Continue Reading

Life sciences briefing: Monday, Oct. 22, 2007

Life sciences briefing: Monday, Oct. 22, 2007

Featured companies: Ablynx, Avant Immunotherapeutics, BioForm Medical, Celldex Therapeutics, Genomas, High-Throughput Genomics, Orchid Cellmark, ReliaGene Technologies, SarCode, TransMolecular, VisEn Medical

UPDATED: Expanded items on SarCode, Celldex/Avant and Ablynx.
UPDATE REDUX: Added items on BioForm Medical, High-Throughput Genomics and Orchid Cellmark/ReliaGene.

San Francisco’s SarCode draws down $7M for inflammation drugs — The… Continue Reading

Life sciences briefing: Thursday, Oct. 18, 2007

Life sciences briefing: Thursday, Oct. 18, 2007

Featured companies: American Oriental Bioengineering, Guangxi Boke, Inspired Technologies, Nanosphere, Patton Medical Devices

UPDATED: Expanded items on Nanosphere and Patton Medical Devices.

Molecular-diagnostics firm Nanosphere sets IPO range, now expects $129M — Northbrook, Ill.-based Nanosphere, a maker of nanotech-derived molecular diagnostics, now expects to raise up to $129 million… Continue Reading

I told you so: Eat your Bioheart out

I told you so: Eat your Bioheart out

(UPDATED: See below.)

I’m not usually one to gloat — oh, who are we kidding? The news today that Bioheart, an oddball “adult” stem-cell company based in Sunrise, Fla., has slashed its IPO price range — essentially halving the company’s value — and fired its underwriters may… Continue Reading