SurModics buys Brookwood Pharma for up to $62M

SurModics, a publicly traded medical-device maker, agreed to acquire Birmingham, Ala.’s Brookwood Pharmaceuticals for $40 million in cash plus milestone payments of up to $22 million. Brookwood develops polymer-based drug formulations. Bloomberg has more here.

For $50M, Water Street gets majority stake in Alpine Biomed

Alpine Biomed, a Fountain Valley, Calif., maker of diagnostic devices, sold a majority stake to the private-equity firm Water Street Healthcare Partners for $50 million, the Chicago Tribune reports. Alpine then used the cash infusion to purchase the neurodiagnostic arm of Medtronic.

Mobius bands together $3.5M for glaucoma

Mobius Therapeutics, a St. Louis developer of glaucoma treatments, raised $3.5 million in a first funding round, VentureWire reports (subscription required). Individual investors provided the cash.

Acrobot jumps into $5M for computer-assisted surgery

London’s Acrobot, a developer of computer-assisted tools for orthopedic surgeries such as knee replacements, raised $5 million (£2.6 million) to launch its first products (PDF link). London Technology Fund and PUK Ventures led the round, joined by Imperial Innovations Group.

Plexus Biomed pulls in $2M for hemorrhoid relief

Plexus Biomedical, an Oakland, Tenn., device maker, raised $2 million in a first round of funding, VentureWire reports (subscription required). The investors were undisclosed investment funds.

Implantable lens maker Eyeonics aims for $86M IPO

Eyeonics, an Aliso Viejo, Calif., developer of implantable lenses for cataract patients, filed to raise as much as $86.25 million in an IPO. The company makes and sells “premium intraocular lenses” that correct vision in addition to replacing a lens obscured by cataracts.

Heart monitor Monebo Tech raises funds

Monebo Technologies, an Austin, Tex., maker of cardiac-monitoring equipment, raised an undisclosed sum (PDF link) in a second funding round. Fairway Medical Technologies, a portfolio company of BCM Technologies, the venture capital subsidiary of Baylor College of Medicine, led the round.

TranS1 aims to relieve lower-back pain with $80.5M IPO

TranS1, a medical-device maker focused on lower-back pain, filed to raise $80.5 million in an IPO. The company makes and markets two products for minimally invasive lumbar spinal fusion, a technique in which surgeons fix, or fuse, two or more vertebrae together in order to minimize the pain from worn-out spinal discs.

Biotech venture funding takes a hit, but devices are hot

Venture-capital financing may be at a six-year high, but the picture in life sciences is a mixed one. After a blowout first quarter, second-quarter fundings in biotechnology actually dropped 19 percent, to $1.1 billion, compared to the same period last year, according to data from Dow Jones VentureOne and Ernst & Young. Medical-device investments, however, were on a tear, with VCs funneling more than $1 billion into the sector during the quarter — the highest total on record.

Ablation Frontiers raises $22M for treating arrythmia

Ablation Frontiers, a Carlsbad, Calif., developer of devices for treating irregular heartbeats known as cardiac arrythmias, raised $21.8 million in a third funding round. The Novartis Venture Fund led the round, joined by Affinity Ventures, Hexagon Investments, Trellis Health Ventures, Versant Ventures, Aberdare Ventures, and Pequot Ventures.

Ouroboros raises $1.2M for spinal devices

OuroBoros, a San Diego developer of devices for minimally invasive spinal fusion, raised $1.17 million in a planned $4 million first funding round, PE Wire reports, citing a regulatory filing. The deal was led by Ascent Medical Ventures.

Amedica sets IPO terms, looks to raise $80.2M for implants

Amedica, a Salt Lake City device maker focused on spine, knee and hip implants, set its IPO terms and now hopes to raise as much as $80.2 million. The company plans to sell up to 5.3 million shares at a price of $13 to $15 apiece.

Satiety pulls in $30M for obesity device

Satiety, a Palo Alto, Calif., device maker focused on obesity, raised $30 million in a fourth round of funding. Skyline Ventures led the round, joined by HLM Venture Partners, Pinnacle Ventures, Venrock, Three Arch Partners, Morgenthaler Ventures and Thomas Fogarty.

Saratoga Ventures raises $3M of $25M fund

Saratoga Ventures, a Los Gatos, Calif., venture-capital firm specializing in early-stage medical-device investments, has raised $3 million as part of an expected $25 million sixth fund, PE Wire reports.

Entrigue Surgical raises $6.3M for ear, nose and throat

Entrigue Surgical, a San Antonio, Tex., medical-devices maker, raised $6.3 million in a first funding round, VentureWire reports (subscription requires), crediting the San Antonio Express-News (no link available). Vertical Group and Prism VentureWorks provided the investment.

NeoMend pulls together $6M for wound healing

NeoMend, an Irvine, Calif., biomaterials company focused on wound care, raised $6 million in a third funding round, VentureWire reports (subscription required). Investors included Prospect Venture Partners, Sanderling Ventures and other unidentified venture capitalists. Four million dollars in bridge loans from Prospect and Sanderling also converted into equity.

FDA clears new uses for Aragon Surgical’s laparascopic device

Aragon Surgical, a Palo Alto, Calif., medical-devices maker, said the FDA cleared its LapCap product for use in general surgery. Aragon, which doesn’t seem to have a Web site, gained ownership of the LapCap when it acquired VeriSure, another device maker, in March.

Stent maker CardioMind raises $33M

CardioMind, a secretive Sunnyvale, Calif., developer of stents designed to prop open blocked arteries, raised $33 million in a third round of funding, VentureWire reports (subscription required). From the VentureWire story:

Syncro raises $300K bridge for magnet-guided feeding tubes

Syncro Medical Innovations, a St. Petersburg, Fla., developer of magnet-assisted feeding tubes, raised $300,000 in a bridge financing leading to an expected $5 million round later this year, VentureWire reports (subscription required). Norwich Ventures provided the financing.

ONI Medical Systems secures $13M for MRI machines

Wilmington, Mass.-based ONI Medical Systems, a developer of new magnetic-resonance imaging systems, raised $12.5 million in a third funding round. Ziegler Meditech Equity Partners led the round, joined by private-equity firms Galen Partners and Ivy Capital Partners.

TissueLink raises $20M for blood-loss products

TissueLink Medical, a Dover, N.H., developer of systems that limit blood loss during surgery, raised $20 million from insiders in a fifth funding round, VentureWire reports (subscription required).

Paracor raises $44M for heart-failure device that restrains the heart

(UPDATED: See below.) Paracor Medical, a Sunnyvale, Calif., startup developing a mesh restraint designed to support failing hearts, raised $44.35 million in a fourth round of funding. The company is vying with another device startup, Acorn Cardiovascular, to prove that this sort of device works and to bring it to market.

U-Systems raises $16.5M for breast ultrasound systems

U-Systems, a San Jose, Calif., maker of ultrasound systems for breast imaging, raised $16.5 million in a fifth round of funding. The company, founded in 1997, markets its systems for the early detection of breast cancer, particularly in women with dense breast tissue.

Generic Medical Devices seeks $10M for, well, generic medical devices

Generic Medical Devices, a Gig Harbor, Wash., company that wants to do for medical devices what generic-drug makers did for pharmaceuticals, is seeking up to $10 million in a first institutional round, VentureWire reports (subscription required). The company, which has previously raised $1.5 million from individual investors, hopes to complete the round later this year.

Medical Carbon Research recapitalizes with $32M, renames itself

Medical Carbon Research Institute, a Austin, Tex., developer of mechanical heart valves, raised $32 million in debt, revenue interest and royalty conversion in a recapitalization that the company said eliminated most of its debt. MCRI also renamed itself after its leading product candidate, and will now be known as On-X Life Technologies.

Boston Scientific acquires medical-wireless startup Remon Medical

Boston Scientific agreed to acquire Remon Medical Technologies, an Israeli maker of wireless technology for communicating with implanted medical devices. The companies didn’t disclose financial terms; their release is here.

Gentis raises $10M for spine-injected implants

Gentis, a Philadelphia developer of an injectable spinal implant, raised $10 million in a first round of funding. Pappas Ventures and Easton Capital led the round, joined by Ivy Capital Partners and Matignon Technologies.

CSA Medical pulls in $8.3M for tissue-ablation device

CSA Medical, a Baltimore developer of endoscopic cryoablation systems, raised $8.3 million in a first round of funding, VentureWire reports (subscription required). New Markets Growth Fund and angel investors provided the funding.

Equipois seeks $1.5M for ergonomic devices

Equipois, a Los Angeles developer of assisted-support devices for the prevention of repetitive stress injury, is partway through raising a $1.5 million first round, VentureWire reports (subscription required). The company plans a larger $10 million round by the end of this year.

Neuromodulator Intelect Medical raises $7M for brain disorders

Intelect Medical, a Cleveland developer of neuromodulation devices for the treatment of brain injury, raised $7 million in a second funding round. The company is currently exploring ways of using deep-brain stimulation, in which implanted electrodes zap particular regions of the brain with calibrated jolts of electricity, in order to rehabilitate brains damaged by injury or stroke. DBS — which is sometimes described as a “pacemaker for the brain” — is currently approved for the treatment of Parkinson’s disease and various forms of tremor.

EndoVention raises $1.5M for clot-removing catheters

San Francisco’s EndoVention, a developer of catheters for use in blood-clot removal, raised $1.5 million of an expected $2.5 million first round, VentureWire reports (subscription required). Such catheters are flexible tubes that doctors can insert into blocked blood vessels in order to “vacuum out” clots, sometimes with the assistances of clot-dissolving drugs. EndoVention’s device has an “expandable mouth” to regulate the intake of clots.

Ringing in the healthcare-reform debate

(UPDATED: See below.) Ever since the Clinton health plan went down in flames 13 years ago, discussion of significant reforms to the U.S. healthcare system has been largely academic. Until now.

Stealthy device maker Thermocure pulls in $125,000

Thermocure, a new Sunnyvale, Calif., medical-device company, raised $125,000 in a first funding round, VentureWire reports. The funding came from Arboretum Ventures.