Life-science briefing: Monday, March 10, 2008

Life-science briefing: Monday, March 10, 2008

TODAY’S HEADLINES:

BrainCells raises $30M for neuroregeneration drugs (release)
EKR Therapeutics takes in $50M plus $95M in debt for pain, heart drugs (release)
Wright Medical acquires Berkeley’s Inbone Tech for $24M (release)
Argolyn Bioscience names Nixon Ellis as CEO (release)

BrainCells raises $30M for neuroregeneration drugs – San Diego’s BrainCells, a… Continue Reading

Science by press release — PrimeGen’s murky stem-cell “breakthrough”

Science by press release — PrimeGen’s murky stem-cell “breakthrough”

Last week, the Irvine, Calif., startup PrimeGen Biotech made a startling claim: It had successfully transformed adult skin, kidney and retina cells into stem cells, without using viral gene therapy that could trigger cancer. That would represent a significant advance over the discovery last year… Continue Reading

Life sciences briefing: Friday, Feb. 15, 2008

Life sciences briefing: Friday, Feb. 15, 2008

TODAY’S HEADLINES:

Q Thera takes in $15M for neural stem-cell treatments (release)
Stroke clotbuster Concentric Medical withdraws IPO (IPOhome)
Avera recaps with $9M to relaunch human tests of GI drug (VentureWire)
Tissue repairer Nerites raises $5.7M (release)
Semafore Pharma aims for $7.5M to launch new cancer-drug trials (VentureWire)
Triage Wireless gets… Continue Reading

Biochip and stem-cell biotech Minerva fires, sues its CEO

Biochip and stem-cell biotech Minerva fires, sues its CEO

A potentially interesting legal drama is unfolding at Minerva Biotechnologies, a Waltham, Mass., startup developing biochips and exploring the biology of cancer stem cells. In a terse release, the company said it has terminated CEO Jim Czirr and launched a search for his successor. Minerva… Continue Reading

Bioroundup: Stem-cell science and money, genetic tests go political, clinical-trial data woes, and more

Bioroundup: Stem-cell science and money, genetic tests go political, clinical-trial data woes, and more

(NOTE: Apologies — especially to RSS readers — if you’ve seen this post before, but an apparent server error ate it late yesterday and I was only able to recover it this morning. Enjoy, or ignore, as seems most fit.)

Featured stories:

Stem-cell science, money and death
Gene… Continue Reading

Life sciences briefing: Thursday, Jan. 17, 2007

Life sciences briefing: Thursday, Jan. 17, 2007

TODAY’S HEADLINES:

TransEnterix gets $21M for minimally invasive GI surgery (release)
Stem-cell developer Bioheart’s IPO postponed (Forbes.com)
Medical-practice software provider AdvancedMD acquired by Francisco Partners (release)
Peptimmune draws $8.2M for MS drug trials (release)
Drug-delivery co. Talima Thera names Martin Babler CEO (release)
Alimera Sciences aims for autumn IPO to fund… Continue Reading

Life sciences briefing: Tuesday, Dec. 11, 2007

Life sciences briefing: Tuesday, Dec. 11, 2007

TODAY’S HEADLINES:

Cancer stem-cell co. OncoMed strikes GSK partnership worth up to $1.4B (release)
Kosmix pulls in $10M for health, lifestyle search (release)
CDI Bioscience pulls in $3M for protein-production improvements (release)
UroMedica takes in $7M for incontinence devices (VentureWire, sub req’d)
Draths raises $2.5M for flu drugs (PE Hub)

Cancer… Continue Reading

Life sciences briefing: Friday, Nov. 30, 2007

Life sciences briefing: Friday, Nov. 30, 2007

Featured companies: Fate Therapeutics, Medgenics, Satoris

UPDATED: Expanded items on Fate Therapeutics and Medgenics. The Satoris item is now a standalone post here.

Fate Therapeutics launches regenerative-medicine quest with $12M — In one of the splashiest launches in recent memory, Seattle’s Fate Therapeutics launched a new regenerative-medicine quest and… Continue Reading

Life sciences briefing: Tuesday, Nov. 27, 2007

Life sciences briefing: Tuesday, Nov. 27, 2007

Featured companies: Bind Biosciences, Clarus Therapeutics, HealOr, HistroRx, Plasticell, SpinalMotion, Xenome, Yaupon Therapeutics

UPDATED: Expanded items on SpinalMotion and Plasticell. Previous items on Evalve and Excaliard have been expanded into standalone posts here and here.

Spinal-disc maker SpinalMotion arranges $14M loan facility — SpinalMotion, a Mountain View, Calif., developer… Continue Reading

Embryonic stem cells without embryos — they’re here

Embryonic stem cells without embryos — they’re here

(UPDATED: See below.)

Two research groups have just reported ways to “reprogram” ordinary cells in ways that cause them to revert into a primordial state resembling that of embryonic stem cells. Those embryonic cells have long been controversial because they’re derived from five-day-old embryos in a destructive… Continue Reading

Stem-cell institute gets a new president, but its management challenges haven’t gone away

Stem-cell institute gets a new president, but its management challenges haven’t gone away

California’s $3 billion stem-cell agency, which has been without a permanent leader since the end of April, finally filled that void yesterday by naming Alan Trounson as its second president.

Hopes are obviously high that the widely respected Australian scientist, pictured at left, can bring… Continue Reading

Life sciences briefing: Thursday, Sept. 13, 2007

Life sciences briefing: Thursday, Sept. 13, 2007

Featured companies: Aldagen, LDR, Lyten Endoscopy, MachLabs, Permatox, TeleMedicine Clinic, ThromboVision

Spinal-implant maker LDR raises $25M — Austin, Texas-based LDR, a maker of spinal implants, raised $25 million in a third funding round. Investors included Telegraph Hill Partners, Austin Ventures, Rothschild Private Equity and PTV Sciences.

LDR sells… Continue Reading

California’s stem-cell management disarray

California’s stem-cell management disarray

(CORRECTED: See below.)

These should be the best of times for California’s $3 billion stem-cell program. Lawsuits that barred the institute from spending its vast sums have been dismissed, serious money has started to flow to scientists, and a $227 million capital-spending project that will build new… Continue Reading

Stem-cell “brain drain” or “brain gain”?

Stem-cell “brain drain” or “brain gain”?

(UPDATED: See below.)

Stem-cell proponents have long told anyone who will listen that U.S. restrictions on the research will lead to a “brain drain” of scientists emigrating to other countries where the work can proceed without limits.

The prospect of the brain drain, though, was always somewhat… Continue Reading

Life sciences briefing: Friday, Aug. 10, 2007

Life sciences briefing: Friday, Aug. 10, 2007

(CORRECTED: See below.)

Featured companies: VistaGen Therapeutics, MindWeavers, Cutanea Life Sciences, Heptares Therapeutics

VistaGen raises $3.75M for stem-cell based drug discovery — South San Francisco, Calif.-based VistaGen Therapeutics, a biotech that uses human embryonic stem cells to discover new drugs, raised $3.75 million in a bridge financing as it… Continue Reading

Novocell: With diabetes study pending, investors pony up another $25M

Novocell: With diabetes study pending, investors pony up another $25M

Novocell, a San Diego embryonic stem-cell company, raised $25 million in a third round of funding. That’s presumably a bit of a letdown for the company, which had previously hoped to pull in as much as $35 million in the round. I wrote earlier about… Continue Reading

Roundup: Biogenerics bill in limbo, clashing data on health IT benefits, the RNAi boom, and more

Roundup: Biogenerics bill in limbo, clashing data on health IT benefits, the RNAi boom, and more

House-Senate confrontation set over biogenerics – Late last month, a key group of senators reached agreement on legislative provisions that would authorize copycat versions of biotech drugs, which are typically complex proteins manufactured by genetically engineered cells (see details here and here). These provisions would finally… Continue Reading

Bioheart: A risky stem-cell company boosts its IPO hopes

Bioheart: A risky stem-cell company boosts its IPO hopes

(UPDATED: See below.)

Sunrise, Fla.-based Bioheart thinks enough of its stem-cell treatment for heart disease that it has just boosted its expected IPO take by $10 million, to $45 million. A close reading of its latest SEC filing, however, raises a fair number of questions for would-be… Continue Reading

Roundup: Guilt-free stem cells, the trials of Avandia, sponsor research bias, news from ASCO, and more

Roundup: Guilt-free stem cells, the trials of Avandia, sponsor research bias, news from ASCO, and more

Flip switch for stem cells – Three research teams reported a technique for “reprogramming” skin cells into embryonic stem cells, those primordial bits of protoplasm that can propagate themselves indefinitely and, under the right conditions, transform themselves into any type of cell in the body. Deriving… Continue Reading

Legal cloud lifts from California stem-cell effort

Legal cloud lifts from California stem-cell effort

The California Supreme Court swept away the last legal impediment to the state’s $3 billion stem-cell research program Wednesday when it declined to review two lawsuits that challenged its constitutionality.

Ideological foes of the state’s stem-cell effort, which voters approved by a large margin in a… Continue Reading