Power Medical Interventions, a Langhorne, Penn., maker of computer-assisted surgical instruments, filed to raise up to $100 million in an IPO. The company develops precisely controlled “endomechanical” cutters and staplers designed to apply consistent and powerful force in both open and minimally invasive surgeries.

Power Medical has incurred cumulative losses of roughly $137 million and envisions those continuing through 2008. Its IPO filing is here; VentureWire (subscription required) has more here.