Soluto, winner of TechCrunch Disrupt New York 2010, has raised $10.5 million in a second round funding from Index Ventures. The company’s software specializes in the tangibly intangible: anti-frustration.

The free software detects the nerve pumping in your forehead by monitoring repeated actions or errors. Once it sees a pattern, it attacks the problem and prevents unnecessary coronaries.

Most interesting is what Soluto is doing with information received from user downloads. Data is collected anonymously and stored in a central database called the “PC Genome.” After analyzing the data, Soluto can see if a particular solution really did relieve frustration and build on that to improve future offerings.

Index Ventures sees the cool factor.  “As technology evolves, it becomes more and more complicated to the end user. There are 1.5 billion PCs around the world. Many of their users are unhappy with them,” said Saul Klein, an Index Ventures partner who is joining Soluto’s board. “We are very excited about Soluto. Their technology is advanced, their data is extremely valuable, and they employ a unique approach to tackling PC and other platforms’ problems through crowdsourcing.”

In combination with existing funding from Bessemer Venture Partners, Giza Venture Capital and Proixma Ventures, Soluto has raised $18.3 million to date. The company plans to use the funds to bring its products to mobile devices, develop new PC solutions and continue making use of the data it collects.

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