U-Systems, a San Jose, Calif., maker of ultrasound systems for breast imaging, raised $16.5 million in a fifth round of funding. The company, founded in 1997, markets its systems for the early detection of breast cancer, particularly in women with dense breast tissue.

Although based in Silicon Valley, the company has strong ties to Taiwan. Siemens Venture Capital led the round, joined by Sycamore Ventures, MDS Capital, Radius Ventures, Kinetic Capital, United Investments of Taiwan, President International Development of Taiwan, iD Innovation (founded by Acer chairman Stan Shih), China Investment & Development of Taiwan, and TSC Bioventures of — you guessed it — Taiwan.

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