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There are well over 25,000 applications now in Apple’s App Store. But there are still a few notable omissions. One of those is the hugely popular Voice over Internet Protocol (VoIP) application Skype. But that could change as soon as next week, GigaOM’s Om Malik has learned.

Citing a “very reliable” source, Malik says the iPhone app for the service could launch next week at the CTIA Wireless conference in Las Vegas. He notes that there have been other clues suggesting such a launch, such as other VoIP services changing potential launches. And that makes sense, because Skype will be the behemoth if it launches on the iPhone.

There are other VoIP apps for the iPhone, such as Truphone and Fring, but judging from their reviews in the App Store, none have really nailed it yet. And people are looking for a reliable way to bypass long-distance calls on their cell phones. Skype already has clients on other mobile platforms, such as Windows Mobile, as Malik points out.

eBay bought Skype in 2005 for just over $4 billion. Recently, eBay has been struggling in the tough economy, but Skype continues to grow. Of course, Google Voice, Google’s recently launched online phone service, could put a damper on that growth.

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