iScience Interventional, maker of surgical tools for eye operations, has closed a prolonged sixth round of funding at $20.5 million after facing a bit more of a challenge due to the economic climate. The money will be used to commercialize its line of micro-catheters used to remove fluid from or deliver medication to the back region of people’s eyes. It hopes to have them on the market by the end of 2010 at the latest, reports VentureWire.

The recent round of financing was led by Johnson & Johnson Development Corp. and included Affinity Capital Management, Clarian Health Ventures, L Capital Partners, Asset Management Company, De Novo Ventures, Prism VentureWorks and Three Arch Ventures. Menlo Park, Calif.-based iScience had previously raised $47 million, the round before this bringing in $20 million in 2007.

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