AliveCor, a startup developing algorithms that detect atrial fibrillation, bradycardia, tachycardia, and other health issues from heart rate readings, today raised $65 million in funding. The company says the money will be used to bolster go-to-market efforts as AliveCor kicks off a partnership with Omron to provide at-home blood pressure monitoring tech to customers.
AliveCor was cofounded by David Albert, a doctor and former chief clinical scientist of cardiology at GE, along with scientists Bruce Satchwell and Kim Barnett. In 2010, Albert demonstrated a prototype of an iPhone ECG through a YouTube video. After the video went viral, he was approached by venture capitalists and partners to fund what became AliveCor.
AliveCor released its first device — an FDA-cleared smartphone case that worked as an ECG — in 2012, followed by a credit card-sized reader. While AliveCor’s first products relied on doctors to analyze the readings, the company received clearances from the FDA in 2015 to provide algorithmic analyses of readings. By 2017, AliveCor’s software was using AI models to “train” its products to identify heart problems. According to the company, the current model contains more than 300,000 parameters (variables internal to the model that determine its predictions) and takes about seven minutes to train on a new user. AliveCor’s platform builds a heart profile of a specific user (including how the electrical system within a heart is firing) after about a month of use.
AliveCor sells a range of products under its Kardia brand that are cleared by the U.S. Food and Drug Administration to capture a “medical-grade” ECG in 30 seconds. They pair to an Android or iOS smartphone to store the ECGs and allow users to email readings to nurses, aids, and primary care physicians. Kardia devices sell for $99 to $150, with some eligible for purchase using an HSA or FSA account. Customers who choose to subscribe to AliveCor’s KardiaCare program ($99 per year or $179 for two years) gain access to additional features, like cardiologist ECG reviews, monthly heart health reports, medication tracking, cloud storage, and discounted device replacements.
AliveCor has partnered with academic institutions to conduct a number of clinical studies, including one with the Cleveland Clinic showing its products could distinguish between atrial fibrillation and normal heart rhythms with high accuracy. In 2017, AliveCor conducted research with Columbia University and the Mayo Clinic to determine whether the company’s hardware could identify early warning signs of Long QT syndrome. And in 2018, AliveCor collaborated with the Mayo Clinic on a study indicating that the KardiaBand could detect hyperkalemia, or elevated levels of potassium in the blood, with 90% to 94% accuracy. AliveCor was granted a “breakthrough device” designation for hyperkalemia detection in September 2018.
AliveCor says it has sold over a million KardiaMobile units and recorded over 85 million ECGs from its customers. Since the pandemic began, Kardia devices have taken nearly 15 million ECGs, an increase of 70% year-over-year.
In response to the pandemic, companies like Current Health and Twistle have also teamed up with Providence and other health care providers to pilot at-home COVID-19-tracking platforms. Beyond the pandemic, investors see lots of potential in digital biomarker monitoring for telehealth. In a case in point, Healx raised $56 million to further develop its AI platform that seeks new drug treatments for rare diseases. And Viz.ai recently secured $50 million for AI that detects early signs of stroke, while Verisim Life closed a $5.2 million seed round to create AI-powered biosimulations that can replace animal drug testing.
Omron led the series E announced today, with participation from Khosla Ventures, WP Global Partners, Qualcomm Ventures, and Bold Capital Partners.